Compared with the original PRP,the MAs induced by ADP,ARA,and EPI decreased in PPP-adjusted PRP (significant at 2-3 times dilution ratio, P 0.05). We also compared the MAs induced by RIS between PRP-obtained-PPP and whole blood-obtained-PPP (2 100Ã- g, 5 min). The maximal aggregation rates (MAs) of different approaches were compared. Platelet aggregation was induced by adenosine diphosphate (ADP),arachidonic acid (ARA),collagen (COL), epinephrine (EPI),or ristocetin (RIS). Platelet-rich plasma (PRP) was diluted using platelet-poor plasma (PPP) and physiological saline (PS),respectively,in a ratio of 1.5,2,2.5 and 3 times. Blood samples from 36 healthy participants aged from 18 to 50 yr. To explore a better method to adjust platelet counts for light transmission aggregometry (LTA). Ling, Li-Qin Yang, Xin-Chun Chen, Hao Liu, Chao-Nan Chen, Si Jiang, Hong Jin, Ya-Xiong Zhou, Jing
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